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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1990-11-7
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pubmed:abstractText |
A girl developed acute agranulocytosis (45/mm3), 37 days after the onset of infectious mononucleosis. The bone marrow showed myeloid hyperplasia with maturation arrest and erythroid hypoplasia. A normal amount of colony forming units of granulocytes and macrophages (CFU-GM) colonies with a relative high number of clusters was observed. Neither anti-neutrophil antibodies nor circulating inhibitors of colony growth were found in serum. Granulocyte and macrophage colony stimulating factor (GM-CSF) activity in the patient's serum rose at this time. The agranulocytosis lasted 5 days and her clinical state soon improved. These results suggested that agranulocytosis was presumably not due to serum factors, including auto-antibodies and/or suppressive substances, and that Epstein-Barr virus (EBV) had some direct or indirect effect on the marrow cells of the myeloid series.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0340-6199
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
149
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
691-4
|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2209660-Agranulocytosis,
pubmed-meshheading:2209660-Bone Marrow,
pubmed-meshheading:2209660-Child, Preschool,
pubmed-meshheading:2209660-Colony-Stimulating Factors,
pubmed-meshheading:2209660-Female,
pubmed-meshheading:2209660-Granulocytes,
pubmed-meshheading:2209660-Humans,
pubmed-meshheading:2209660-Infectious Mononucleosis,
pubmed-meshheading:2209660-Macrophages
|
pubmed:year |
1990
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pubmed:articleTitle |
Agranulocytosis following infectious mononucleosis.
|
pubmed:affiliation |
Department of Paediatrics, Sumitomo Hospital, Osaka, Japan.
|
pubmed:publicationType |
Journal Article,
Case Reports
|