Linked Life Data

2208093

Source:http://linkedlifedata.com/resource/pubmed/id/2208093

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1990-11-20
pubmed:abstractText
The staining characteristics of monoclonal antibodies (MAb) are often determined on small numbers of biopsies. The true staining profile can only properly be determined when large numbers of biopsies are stained. We have examined the staining profile of 24K MAb on 146 benign breast biopsies. The staining characteristics were then grouped according to whether the patients were at high or low risk of breast cancer by current epidemiological or radiological risk criteria. This was done to detect whether 24K MAb could be used as a marker of cancer risk. Only Wolfe coded risk criteria showed staining differences between the two risk categories. Cytoplasmic staining was more common in the low risk Wolfe coded groups (P = 0.03, Fisher's exact test). We recommend that further studies be undertaken to evaluate the role of 24K MAb as a marker of cancer risk.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
75-80
pubmed:dateRevised
2009-9-29
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Evaluation of immunohistochemical staining of breast tissue by an oestrogen-regulated protein, 24K according to epidemiological and radiological breast cancer risk criteria.
pubmed:affiliation
Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't