Linked Life Data

2207107

Source:http://linkedlifedata.com/resource/pubmed/id/2207107

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
31
pubmed:dateCreated
1990-11-20
pubmed:abstractText
We have investigated the effects of methanol, ethanol, and 1-propanol on the phase transitions of L-alpha-dimyristoylphosphatidylethanolamine using differential scanning calorimetry and Fourier transform infrared spectroscopy. Alcohols lower the temperature of the gel (L beta) to liquid-crystalline (L alpha) phase transition and also lower the temperature of the unhydrated crystalline (Lc) to liquid-crystalline phase transition. When the lipid/alcohol dispersions are incubated at 2 degrees C for 1-18 h, a dehydrated crystalline phase forms, which gives rise to a phase transition at about 55 degrees C. This dehydrated crystalline phase forms more quickly at higher alcohol concentrations. Although alcohol at low concentration lowers the enthalpy of the observed melting transition, at high concentrations 1-propanol markedly increases this enthalpy. The phase giving rise to this high-enthalpy melting process is distinct from both the unhydrated crystalline phase and the gel phase. Infrared spectra suggest that this phase contains significant amounts of alcohol in a solid solution with the lipid.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0006-2960
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
29
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7289-96
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Interactions of short-chain alcohols with dimyristoylphosphatidylethanolamine bilayers: a calorimetric and infrared spectroscopic investigation.
pubmed:affiliation
Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, D.C. 20306-6000.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.