pubmed-article:2206788 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2206788 | lifeskim:mentions | umls-concept:C0221102 | lld:lifeskim |
pubmed-article:2206788 | lifeskim:mentions | umls-concept:C0026140 | lld:lifeskim |
pubmed-article:2206788 | lifeskim:mentions | umls-concept:C0078847 | lld:lifeskim |
pubmed-article:2206788 | pubmed:issue | 2 | lld:pubmed |
pubmed-article:2206788 | pubmed:dateCreated | 1990-11-21 | lld:pubmed |
pubmed-article:2206788 | pubmed:abstractText | 1. The excretion of zopiclone into breast milk was studied in 12 lactating women in the early postpartum period following the oral administration of a single zopiclone tablet (7.5 mg). 2. The milk/plasma AUC ratio of zopiclone was 0.51 +/- 0.09 (mean +/- s.d.). Individual mean milk/plasma concentration ratios of zopiclone showed significant interindividual variation (range 0.41-0.70). 3. A comparison of pharmacokinetic parameters in the postpartum women with those reported previously in non-pregnant women, showed significantly higher Cmax values in the lactating mothers; tmax occurred later in milk than in maternal plasma. 4. Assuming a daily milk intake of 0.15 l kg-1 and 100% absorption the average infant dose of zopiclone in milk would be 1.4% of the weight adjusted dose ingested by the mother. | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:language | eng | lld:pubmed |
pubmed-article:2206788 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2206788 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2206788 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2206788 | pubmed:month | Aug | lld:pubmed |
pubmed-article:2206788 | pubmed:issn | 0306-5251 | lld:pubmed |
pubmed-article:2206788 | pubmed:author | pubmed-author:SandeH AHA | lld:pubmed |
pubmed-article:2206788 | pubmed:author | pubmed-author:MathesonII | lld:pubmed |
pubmed-article:2206788 | pubmed:author | pubmed-author:GaillotJJ | lld:pubmed |
pubmed-article:2206788 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2206788 | pubmed:volume | 30 | lld:pubmed |
pubmed-article:2206788 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2206788 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2206788 | pubmed:pagination | 267-71 | lld:pubmed |
pubmed-article:2206788 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:meshHeading | pubmed-meshheading:2206788-... | lld:pubmed |
pubmed-article:2206788 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2206788 | pubmed:articleTitle | The excretion of zopiclone into breast milk. | lld:pubmed |
pubmed-article:2206788 | pubmed:affiliation | Department of Pharmacotherapeutics, University of Oslo, Norway. | lld:pubmed |
pubmed-article:2206788 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2206788 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2206788 | lld:pubmed |