pubmed-article:2205529 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2205529 | lifeskim:mentions | umls-concept:C0030274 | lld:lifeskim |
pubmed-article:2205529 | lifeskim:mentions | umls-concept:C0521425 | lld:lifeskim |
pubmed-article:2205529 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
pubmed-article:2205529 | lifeskim:mentions | umls-concept:C1842402 | lld:lifeskim |
pubmed-article:2205529 | lifeskim:mentions | umls-concept:C2827424 | lld:lifeskim |
pubmed-article:2205529 | pubmed:issue | 7 | lld:pubmed |
pubmed-article:2205529 | pubmed:dateCreated | 1990-10-26 | lld:pubmed |
pubmed-article:2205529 | pubmed:abstractText | Exocrine pancreatic marker (immunoreactive-trypsin) and endocrine Beta-cell function (plasma insulin and C-peptide during an oral glucose tolerance test) were studied in 40 subjects with tropical-calcific-pancreatitis [seven non-diabetic, seven with impaired-glucose-tolerance and 26 diabetic (fibro-calculous-pancreatic-diabetes)]. In non-diabetic and impaired-glucose-tolerance subjects there was evidence of active pancreatitis in some and exocrine function was partially preserved. Fibro-calculous-pancreatic-diabetic subjects showed severely diminished exocrine pancreatic function; none showed 'pancreatitic' elevation of immunoreactive-trypsin. Beta-cell function was preserved in non-diabetic and impaired-glucose-tolerance subjects; diabetic subjects showed variable Beta-cell function but it was severely diminished in more than 75%. Immunoreactive-trypsin and C-peptide were directly correlated (rs = 0.55, p less than 0.01). This cross sectional study demonstrates, for the first time, that the Beta-cell loss in tropical-calcific-pancreatitis is related to the exocrine loss. It suggests that diabetes in tropical-calcific-pancreatitis is either secondary to pancreatitis or that a common factor(s) acts simultaneously on both components. | lld:pubmed |
pubmed-article:2205529 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:language | eng | lld:pubmed |
pubmed-article:2205529 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:2205529 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2205529 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2205529 | pubmed:month | Jul | lld:pubmed |
pubmed-article:2205529 | pubmed:issn | 0012-186X | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:AlbertiK GKG | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:HockadayT DTD | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:DandonaPP | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:NaikS SSS | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:YaoM JMJ | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:YajnikC SCS | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:ShelgikarK... | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:KatrakAA | lld:pubmed |
pubmed-article:2205529 | pubmed:author | pubmed-author:SahasrabudheR... | lld:pubmed |
pubmed-article:2205529 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2205529 | pubmed:volume | 33 | lld:pubmed |
pubmed-article:2205529 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2205529 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2205529 | pubmed:pagination | 417-21 | lld:pubmed |
pubmed-article:2205529 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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pubmed-article:2205529 | pubmed:year | 1990 | lld:pubmed |
pubmed-article:2205529 | pubmed:articleTitle | The spectrum of pancreatic exocrine and endocrine (beta-cell) function in tropical calcific pancreatitis. | lld:pubmed |
pubmed-article:2205529 | pubmed:affiliation | Wellcome Diabetes Study, King Edward Memorial Hospital, Pune, India. | lld:pubmed |
pubmed-article:2205529 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2205529 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2205529 | lld:pubmed |