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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-9-10
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pubmed:abstractText |
We have compared the effects of aztreonam and placebo in the prevention of urinary tract infections (UTI) in elderly hospitalized patients who needed urethral catheterization. 162 patients (96 males, 66 females; age range 60-91 years) were randomly allocated to receive double-blind a single dose of aztreonam (2 g i.m. 80 patients) or placebo (4 ml lidocaine 2%, 82 patients) three hours before catheterization. All patients were followed-up for 7 days. Urine culture was performed before, at the first, third and seventh day of catheterization. At the end of follow-up 71/80 patients (88.7%) who received a single preventing dose of aztreonam had negative urine culture without clinical signs of UTI. On the contrary, in the group treated with placebo at the end of follow-up only 38/82 patients (46.3%) had negative urine without clinical signs of UTI. In conclusion, our data suggest that a single 2g i.m. dose of aztreonam is effective in preventing UTI in elderly patients needing indwelling urethral catheterization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1120-009X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
178-81
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pubmed:dateRevised |
2009-8-4
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pubmed:meshHeading |
pubmed-meshheading:2199628-Aged,
pubmed-meshheading:2199628-Aged, 80 and over,
pubmed-meshheading:2199628-Aztreonam,
pubmed-meshheading:2199628-Diabetes Complications,
pubmed-meshheading:2199628-Double-Blind Method,
pubmed-meshheading:2199628-Female,
pubmed-meshheading:2199628-Humans,
pubmed-meshheading:2199628-Male,
pubmed-meshheading:2199628-Middle Aged,
pubmed-meshheading:2199628-Randomized Controlled Trials as Topic,
pubmed-meshheading:2199628-Urinary Catheterization,
pubmed-meshheading:2199628-Urinary Tract Infections
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pubmed:year |
1990
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pubmed:articleTitle |
A single dose of aztreonam in the prevention of urinary tract infections in elderly catheterized patients.
|
pubmed:affiliation |
Cattedra di Patologia Speciale Medica, University of Brescia, Italy.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|