Linked Life Data

2195969

Source:http://linkedlifedata.com/resource/pubmed/id/2195969

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-8-13
pubmed:abstractText
The incidence of meningococcal infections undergoes secular variations with modifications in the distribution of identified serotypes. Rhinopharyngeal carriage of meningococci, common in the community, is the natural means of immunization. Prevalence of this carriage varies across age groups and communities, as well as according to whether or not cases are present in the community under study. Identified factors that promote transmission of the bacteria include crowded living conditions, poor socioeconomic conditions, and, more controversially, respiratory tract viral infections. Development of meningococcal infection usually occurs within seven days of onset of carriage. Secondary cases account for approximately 3% of meningococcal infections in France. The risk of development of secondary cases is increased in subjects sharing the patient's home or exposed to his or her rhinopharyngeal secretions. Prevention of these secondary cases rests on chemoprophylaxis and immunization. The qualities of antimicrobial agents proposed for chemoprophylaxis are discussed, with special emphasis on spiramycin and rifampin which are the most widely used. This study, which rests on French epidemiologic surveillance findings and data from a review of the literature, forms the basis for new French guidelines.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0066-2097
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
209-18
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Epidemiology of meningococcal infections and principles for the prevention of secondary cases].
pubmed:affiliation
Direction Générale de la Santé, Bureau des maladies transmissibles, Paris.
pubmed:publicationType
Journal Article, English Abstract, Review