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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1990-8-15
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pubmed:abstractText |
Fetal macrosomia occurs despite nearly normal maternal blood glucose levels in women with diabetes treated with insulin. We examined the hypothesis that it may be caused by insulin transferred as an insulin-antibody complex from the mother to her fetus. We adapted and validated a method based on high-performance liquid chromatography and used it to quantitate insulin in small volumes (0.5 to 1.0 ml) of cord serum from 51 infants born to mothers with insulin-dependent diabetes mellitus.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0028-4793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
323
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
309-15
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2195347-Adult,
pubmed-meshheading:2195347-Amniotic Fluid,
pubmed-meshheading:2195347-Antibody Formation,
pubmed-meshheading:2195347-Antigen-Antibody Complex,
pubmed-meshheading:2195347-Blood Glucose,
pubmed-meshheading:2195347-Chromatography, High Pressure Liquid,
pubmed-meshheading:2195347-Diabetes Mellitus, Type 1,
pubmed-meshheading:2195347-Female,
pubmed-meshheading:2195347-Fetal Blood,
pubmed-meshheading:2195347-Fetal Macrosomia,
pubmed-meshheading:2195347-Humans,
pubmed-meshheading:2195347-Infant, Newborn,
pubmed-meshheading:2195347-Insulin,
pubmed-meshheading:2195347-Insulin Antibodies,
pubmed-meshheading:2195347-Maternal-Fetal Exchange,
pubmed-meshheading:2195347-Pregnancy,
pubmed-meshheading:2195347-Pregnancy in Diabetics
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pubmed:year |
1990
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pubmed:articleTitle |
Transplacental passage of insulin in pregnant women with insulin-dependent diabetes mellitus. Its role in fetal macrosomia.
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pubmed:affiliation |
Division of Endocrinology, University of Cincinnati Medical Center.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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