rdf:type |
|
lifeskim:mentions |
umls-concept:C0018787,
umls-concept:C0018801,
umls-concept:C0026336,
umls-concept:C0027051,
umls-concept:C0085104,
umls-concept:C0205263,
umls-concept:C0205314,
umls-concept:C0206131,
umls-concept:C0277785,
umls-concept:C0679622,
umls-concept:C1522424
|
pubmed:issue |
11 Suppl
|
pubmed:dateCreated |
2011-9-13
|
pubmed:abstractText |
A drug delivery system that constitutively and effectively retains cardioprotective reagents in the targeted myocardium has long been sought to treat acute myocardial infarction. We hypothesized that a scaffold-free induced adipocyte cell-sheet (iACS), transplanted on the surface of the heart, might intramyocardially secrete multiple cardioprotective factors including adiponectin (APN), consequently attenuating functional deterioration after acute myocardial infarction.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
1524-4539
|
pubmed:author |
pubmed-author:DaimonTakashiT,
pubmed-author:FukushimaSatsukiS,
pubmed-author:HirataAyumuA,
pubmed-author:ImanishiYukikoY,
pubmed-author:Kitagawa-SakakidaSatoruS,
pubmed-author:MaedaNorikazuN,
pubmed-author:MiyagawaShigeruS,
pubmed-author:OkanoTeruoT,
pubmed-author:SawaYoshikiY,
pubmed-author:ShimizuTatsuyaT,
pubmed-author:ShimomuraIichiroI
|
pubmed:issnType |
Electronic
|
pubmed:day |
13
|
pubmed:volume |
124
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
S10-7
|
pubmed:meshHeading |
pubmed-meshheading:21911798-Adipocytes,
pubmed-meshheading:21911798-Adiponectin,
pubmed-meshheading:21911798-Animals,
pubmed-meshheading:21911798-Cardiotonic Agents,
pubmed-meshheading:21911798-Cardiovascular Surgical Procedures,
pubmed-meshheading:21911798-Drug Delivery Systems,
pubmed-meshheading:21911798-Heart,
pubmed-meshheading:21911798-Heart Failure,
pubmed-meshheading:21911798-Hepatocyte Growth Factor,
pubmed-meshheading:21911798-Male,
pubmed-meshheading:21911798-Mice,
pubmed-meshheading:21911798-Mice, Inbred C57BL,
pubmed-meshheading:21911798-Mice, Knockout,
pubmed-meshheading:21911798-Models, Animal,
pubmed-meshheading:21911798-Myocardial Infarction,
pubmed-meshheading:21911798-Tissue Therapy,
pubmed-meshheading:21911798-Treatment Outcome,
pubmed-meshheading:21911798-Vascular Endothelial Growth Factor A,
pubmed-meshheading:21911798-Ventricular Remodeling
|
pubmed:year |
2011
|
pubmed:articleTitle |
Induced adipocyte cell-sheet ameliorates cardiac dysfunction in a mouse myocardial infarction model: a novel drug delivery system for heart failure.
|
pubmed:affiliation |
Department of Cardiovascular Surgery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|