Linked Life Data

21904518

Source:http://linkedlifedata.com/resource/pubmed/id/21904518

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2011-9-9
pubmed:abstractText
ALTHOUGH THE PATHOGENESIS OF AUTOIMMUNE PANCREATITIS REMAINS UNCLEAR, THIS REPORT PRESENTS RECENT EVIDENCE OF THE CLINICAL ASPECTS OF THIS DISEASE: mild abdominal symptoms, usually without acute attacks of pancreatitis; occasional presence of obstructive jaundice; elevated levels of serum gammaglobulin, immunoglobulin (Ig)G, or IgG4; presence of autoantibodies; diffuse enlargement of the pancreas; irregular narrowing of the pancreatic duct (sclerosing pancreatitis), often with intrapancreatic biliary stenosis or coexisting biliary lesions (sclerosing cholangitis similar to primary sclerosing cholangitis) seen on endoscopic retrograde cholangiopancreatography; fibrotic changes with lymphocyte and IgG4-positive plasmacyte infiltration and obliterative phlebitis; occasional association with other systemic lesions (such as sialadenitis), retroperitoneal fibrosis, and interstitial renal tubular disorders; and response to steroid therapy. Based upon these findings, several sets of diagnostic criteria have been proposed. Further studies and international consensus for diagnostic criteria and pathogenetic mechanisms are needed.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jun
pubmed:issn
1554-7914
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
417-26
pubmed:year
2008
pubmed:articleTitle
Recent advances in autoimmune pancreatitis.
pubmed:affiliation
Dr. Okazaki serves as Chairman and Professor in The Third Department of Internal Medicine at Kansai Medical University in Osaka, Japan, and Director of the Department of Gastroenterology and Hepatology at Kansai Medical University Hirakata Hospital, also in Osaka, Japan.
pubmed:publicationType
Journal Article