Source:http://linkedlifedata.com/resource/pubmed/id/21899217
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
303
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pubmed:dateCreated |
2011-9-8
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pubmed:abstractText |
Lynch syndrome is an autosomal dominant disease associated with an important risk of cancer, mainly endometrial and colorectal-cancer. This risk can be efficiently lessen by an appropriate screening as far as the mutations carriers are identified. As current clinicopathological recommendations lack sensitivity, a systematic pre-screening of every patient with a colorectal or endometrial cancer can be proposed. Oncogenetic units of the HUG in Geneva and ICHV in Valais have set up a population-based study to evaluate the efficacy of such a strategy. Whatever the approach, the pathologist is directly implicated as Lynch syndrome harbors specific histological aspects that can help to its identification, but also as pre-screening tests are directly realized on tumor-tissue.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1660-9379
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1502-6
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pubmed:meshHeading | |
pubmed:year |
2011
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pubmed:articleTitle |
[Lynch syndrome: when pathologist and clinician have the opportunity to reduce the risk of developing cancer].
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pubmed:affiliation |
Service de pathologie clinique, Département de médecine génétique et de laboratoire, HUG, Genève. Muriel.Genevay@hcuge.ch
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pubmed:publicationType |
Journal Article,
English Abstract
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