Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
303
pubmed:dateCreated
2011-9-8
pubmed:abstractText
Lynch syndrome is an autosomal dominant disease associated with an important risk of cancer, mainly endometrial and colorectal-cancer. This risk can be efficiently lessen by an appropriate screening as far as the mutations carriers are identified. As current clinicopathological recommendations lack sensitivity, a systematic pre-screening of every patient with a colorectal or endometrial cancer can be proposed. Oncogenetic units of the HUG in Geneva and ICHV in Valais have set up a population-based study to evaluate the efficacy of such a strategy. Whatever the approach, the pathologist is directly implicated as Lynch syndrome harbors specific histological aspects that can help to its identification, but also as pre-screening tests are directly realized on tumor-tissue.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1660-9379
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1502-6
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
[Lynch syndrome: when pathologist and clinician have the opportunity to reduce the risk of developing cancer].
pubmed:affiliation
Service de pathologie clinique, Département de médecine génétique et de laboratoire, HUG, Genève. Muriel.Genevay@hcuge.ch
pubmed:publicationType
Journal Article, English Abstract