Linked Life Data

2188931

Source:http://linkedlifedata.com/resource/pubmed/id/2188931

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-7-5
pubmed:abstractText
Using Bayesian and decision analytical concepts, we can define the ideal characteristics of any screening test for cancer of the prostate: high specificity, reasonably high sensitivity, noninvasiveness, low cost, and low interobserver variability. Computed tomography (CT) fails as a test, since it cannot show the internal structure of the prostate; MRI is too expensive and has an unacceptably poor specificity. Transrectal sonography does have many desirable characteristics, including relatively high sensitivity and, if no biopsy is done, low cost and noninvasiveness. But it has an unacceptably low specificity for early, clinically significant lesions: over half of all patients tested will have a positive result, requiring a confirming biopsy, which means that transrectal sonography will in the end be too invasive and too expensive. Therefore, we cannot recommend transrectal sonography as a primary screening tool for cancer of the prostate at this time.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0020-9996
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
591-5
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
The role of imaging in screening for prostate cancer. A decision analysis perspective.
pubmed:affiliation
Department of Diagnostic Radiology and Nuclear Medicine, Stanford University, Palo Alto, CA.
pubmed:publicationType
Journal Article, Comparative Study