Linked Life Data

218848

Source:http://linkedlifedata.com/resource/pubmed/id/218848

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1979-6-29
pubmed:abstractText
Receptors for various hormones have been examined throughout the adult life span. In most of these studies receptor concentrations were found to decrease with increasing age, either during senescence or earlier in adulthood. In contrast, binding affinities did not change with age. Tissues and cells examined have included liver, brain, adipose tissue, skeletal muscle, prostate, fibroblasts, and lymphocytes. Receptors for steroids as well as membrane-active hormones such as insulin, glucagon, catecholamines, and prolactin were studied. Rats, mice, dogs, and humans have been employed. Changes in hormone receptor levels appear to constitute a common manifestation of the aging process, and offer interesting model systems in which to study the control of genetic expression during senescence.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0014-9446
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1910-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Hormone receptor changes during adulthood and senescence: significance for aging research.
pubmed:publicationType
Journal Article