Source:http://linkedlifedata.com/resource/pubmed/id/21876096
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
2011-8-30
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pubmed:abstractText |
Gene transfer to cardiomyocytes in vivo has received much research attention in the last decade but remains a substantial hurdle. Gene transfer using ultrasound-targeted microbubble destruction is a promising tool for gene therapy. Little data have shown the feasibility and optimization of this method for primary myocardial disease. In this study, we sought to determine the feasibility and efficiency of in vivo gene transfer to the myocardium mediated by ultrasound-targeted microbubble destruction accompanied by polyethylenimine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1550-9613
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
30
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1247-58
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pubmed:meshHeading |
pubmed-meshheading:21876096-Analysis of Variance,
pubmed-meshheading:21876096-Animals,
pubmed-meshheading:21876096-Feasibility Studies,
pubmed-meshheading:21876096-Gene Therapy,
pubmed-meshheading:21876096-Gene Transfer Techniques,
pubmed-meshheading:21876096-Liposomes,
pubmed-meshheading:21876096-Male,
pubmed-meshheading:21876096-Mice,
pubmed-meshheading:21876096-Mice, Inbred BALB C,
pubmed-meshheading:21876096-Microbubbles,
pubmed-meshheading:21876096-Myocytes, Cardiac,
pubmed-meshheading:21876096-Plasmids,
pubmed-meshheading:21876096-Polyethyleneimine,
pubmed-meshheading:21876096-Sonication
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pubmed:year |
2011
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pubmed:articleTitle |
Ultrasound- and liposome microbubble-mediated targeted gene transfer to cardiomyocytes in vivo accompanied by polyethylenimine.
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pubmed:affiliation |
Department of Medical Imaging Center, First Affiliated Hospital, Jinan University, 613 Huangpu Dadao Xi, 510632 Guangzhou, Guangdong, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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