| pubmed-article:2186967 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0812202 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C2697656 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0175697 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0033634 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0205374 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:2186967 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:2186967 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2186967 | pubmed:dateCreated | 1990-6-15 | lld:pubmed |
| pubmed-article:2186967 | pubmed:abstractText | We reported previously that Ets2 is expressed in normal and transformed macrophages. We show here that the expression of both c-ets-2 mRNA proteins is induced rapidly and transiently in chicken nondividing bone marrow-derived macrophages but not in E26-transformed myeloblasts in response to chicken myelomonocytic growth factor (cMGF), an avian hematopoietic growth factor required for survival, proliferation, and colony formation of avian myeloid cells. c-ets-2 expression is also rapidly induced in chicken bone marrow-derived macrophages, human monocytes, and mouse peritoneal macrophages in response to LPS and/or PKC activators. The rapid induction of Ets2 after treatment of chicken bone marrow-derived macrophages by cMGF is blunted after down-regulation or inactivation of PKC, suggesting a role of PKC in the cMGF-induced signal transduction pathway. Because Ets2 is localized in the nucleus of macrophages and binds to DNA in vitro, the kinetics of its expression suggest a role for Ets2 in the transduction within the nucleus of specific signals received at the cell membrane and involved in securing the survival and/or the development of functional competence of these cells. | lld:pubmed |
| pubmed-article:2186967 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2186967 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2186967 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2186967 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2186967 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2186967 | pubmed:issn | 0890-9369 | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:BaillyMM | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:GhysdaelJJ | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:LagrouCC | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:SaribanEE | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:PognonecPP | lld:pubmed |
| pubmed-article:2186967 | pubmed:author | pubmed-author:BoulukosK EKE | lld:pubmed |
| pubmed-article:2186967 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2186967 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:2186967 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2186967 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2186967 | pubmed:pagination | 401-9 | lld:pubmed |
| pubmed-article:2186967 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:2186967 | pubmed:year | 1990 | lld:pubmed |
| pubmed-article:2186967 | pubmed:articleTitle | Rapid and transient expression of Ets2 in mature macrophages following stimulation with cMGF, LPS, and PKC activators. | lld:pubmed |
| pubmed-article:2186967 | pubmed:affiliation | Institut de la Santé et de la Recherche Médicale U 186/Centre National de la Recherche Scientifique, UA 041160, Institut Pasteur, Lille, France. | lld:pubmed |
| pubmed-article:2186967 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2186967 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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