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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2011-9-2
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pubmed:abstractText |
The incidence and prevalence of gastroenteropancreatic neuroendocrine tumors has been increasing over the past 3 decades. Because of high densities of somatostatin receptors (sstr)--mainly sstr-2--on the cell surface of these tumors, (111)In-diethylenetriaminepentaacetic acid-octreotide scintigraphy has become an important part of clinical management. (18)F-radiolabeled analogs with suitable pharmacokinetics would permit PET with more rapid clinical protocols.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1535-5667
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1441-8
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pubmed:meshHeading |
pubmed-meshheading:21852355-Animals,
pubmed-meshheading:21852355-Female,
pubmed-meshheading:21852355-Mice,
pubmed-meshheading:21852355-Mice, Inbred BALB C,
pubmed-meshheading:21852355-Neoplasm Transplantation,
pubmed-meshheading:21852355-Neoplasms, Experimental,
pubmed-meshheading:21852355-Octreotide,
pubmed-meshheading:21852355-Organometallic Compounds,
pubmed-meshheading:21852355-Polyethylene Glycols,
pubmed-meshheading:21852355-Positron-Emission Tomography,
pubmed-meshheading:21852355-Radiopharmaceuticals,
pubmed-meshheading:21852355-Receptors, Somatostatin,
pubmed-meshheading:21852355-Structure-Activity Relationship,
pubmed-meshheading:21852355-Substrate Specificity,
pubmed-meshheading:21852355-Tissue Distribution
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pubmed:year |
2011
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pubmed:articleTitle |
Targeting somatostatin receptors: preclinical evaluation of novel 18F-fluoroethyltriazole-Tyr3-octreotate analogs for PET.
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pubmed:affiliation |
Comprehensive Cancer Imaging Center at Imperial College, Faculty of Medicine, Imperial College London, London, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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