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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-9-8
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pubmed:abstractText |
Aortic stenosis (AS) and diabetes mellitus (DM) are frequent comorbidities in aging populations. In heart failure, DM worsens diastolic left ventricular (LV) dysfunction, thereby adversely affecting symptoms and prognosis. Effects of DM on diastolic LV function were therefore assessed in aortic stenosis, and underlying myocardial mechanisms were identified.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4539
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pubmed:author |
pubmed-author:BorbélyAttilaA,
pubmed-author:Falcão-PiresInêsI,
pubmed-author:GavinaCristinaC,
pubmed-author:HamdaniNazhaN,
pubmed-author:Leite-MoreiraAdelino FAF,
pubmed-author:NiessenHans W MHW,
pubmed-author:PaulusWalter JWJ,
pubmed-author:SchalkwijkCasper GCG,
pubmed-author:StienenGer J MGJ,
pubmed-author:van HeerebeekLoekL,
pubmed-author:van der VeldenJolandaJ
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pubmed:issnType |
Electronic
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pubmed:day |
6
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1151-9
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pubmed:meshHeading |
pubmed-meshheading:21844073-Aged,
pubmed-meshheading:21844073-Aortic Valve Stenosis,
pubmed-meshheading:21844073-Biopsy,
pubmed-meshheading:21844073-Collagen,
pubmed-meshheading:21844073-Coronary Circulation,
pubmed-meshheading:21844073-Diabetes Mellitus, Type 2,
pubmed-meshheading:21844073-Echocardiography, Doppler,
pubmed-meshheading:21844073-Female,
pubmed-meshheading:21844073-Fibrosis,
pubmed-meshheading:21844073-Glycosylation End Products, Advanced,
pubmed-meshheading:21844073-Heart Rate,
pubmed-meshheading:21844073-Humans,
pubmed-meshheading:21844073-Male,
pubmed-meshheading:21844073-Middle Aged,
pubmed-meshheading:21844073-Muscle Proteins,
pubmed-meshheading:21844073-Protein Kinases,
pubmed-meshheading:21844073-Sarcomeres,
pubmed-meshheading:21844073-Ventricular Dysfunction, Left
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pubmed:year |
2011
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pubmed:articleTitle |
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.
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pubmed:affiliation |
Department of Physiology, VU University Medical Center Amsterdam, Van der Boechorststraat 7,1081BT Amsterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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