Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1990-5-25
pubmed:abstractText
The echocardiograms and clinical records of 70 patients with infective endocarditis seen between 1983 and 1988 were examined to evaluate the role of two-dimensional and Doppler echocardiography in the diagnosis of infective endocarditis and identify risk factors for morbidity and mortality. A blinded observer reviewed the echocardiograms for the presence and size of vegetations and the severity of the valvular regurgitation. Vegetations were identified in 54 (78%) of 69 technically satisfactory echocardiograms. In 38 patients whose heart was examined at surgery or autopsy, all vegetations diagnosed by echocardiography were confirmed, but six additional vegetations were found. Abnormal (greater than or equal to 2+) valvular regurgitation was present in 88% of patients. No patient with less than or equal to 1+ regurgitation (n = 8) died or required valve surgery for heart failure, but three of the eight patients did undergo surgery for mycotic aneurysm, recurrent embolism or paravalvular abscess. In patients without embolism before echocardiography, there was a trend toward a greater incidence of subsequent embolism in those with vegetations greater than 10 mm in size (26% [8 of 31] compared with 11% [2 of 18] with vegetations less than or equal to 10 mm) (p = 0.19). By multivariate analysis, risk factors for in-hospital death (n = 7) were an infected prosthetic valve (p less than 0.007), systemic embolism (p less than 0.02) and infection with Staphylococcus aureus (p = 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0735-1097
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1227-33
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:2184183-Abscess, pubmed-meshheading:2184183-Adolescent, pubmed-meshheading:2184183-Adult, pubmed-meshheading:2184183-Aged, pubmed-meshheading:2184183-Aged, 80 and over, pubmed-meshheading:2184183-Echocardiography, pubmed-meshheading:2184183-Embolism, pubmed-meshheading:2184183-Endocarditis, Bacterial, pubmed-meshheading:2184183-Heart Valve Diseases, pubmed-meshheading:2184183-Heart Valve Prosthesis, pubmed-meshheading:2184183-Humans, pubmed-meshheading:2184183-Middle Aged, pubmed-meshheading:2184183-Observer Variation, pubmed-meshheading:2184183-Randomized Controlled Trials as Topic, pubmed-meshheading:2184183-Retrospective Studies, pubmed-meshheading:2184183-Risk Factors, pubmed-meshheading:2184183-Staphylococcal Infections, pubmed-meshheading:2184183-Streptococcal Infections, pubmed-meshheading:2184183-Survival Rate
pubmed:year
1990
pubmed:articleTitle
Infective endocarditis, 1983-1988: echocardiographic findings and factors influencing morbidity and mortality.
pubmed:affiliation
Department of Medicine, University of Washington, Seattle 98195.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Research Support, Non-U.S. Gov't