Linked Life Data

21828240

Source:http://linkedlifedata.com/resource/pubmed/id/21828240

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2011-8-15
pubmed:abstractText
The transcription factor B-Myb plays a critical role in regulating gene expression and is implicated in controlling carcinogenesis and cellular senescence. Transcription of the B-Myb gene is regulated by retinoblastoma proteins acting directly on the B-Myb promoter. Recently, we found that microRNAs also control the abundance of B-Myb mRNA during senescence, adding another level of complexity to B-Myb regulation. This review focuses on the importance of B-Myb in cancer and senescence, with an emphasis on the regulation of B-Myb expression and activity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1538-7445
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
5370-3
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
B-Myb, cancer, senescence, and microRNAs.
pubmed:affiliation
Department of Genetics and Yale Comprehensive Cancer Center, Yale School of Medicine, New Haven, Connecticut 06520-8005, USA.
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural