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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1979-5-26
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pubmed:abstractText |
Cytotoxic T lymphocytes (CTLs) can be generated if spleen cells from reovirus-infected mice are stimulated in vitro with syngeneic reovirus-infected cells. These cytolytic effector cells demonstrate: (i) serotype specificity (i.e., maximal cytolytic activity is observed on target cells infected with the serotype used to induce the CTLs) and (ii) H-2 restriction. The SI gene was shown to be the predominant viral gene determining the specificity of the cytotoxic T cells. This genome segment has previously been demonstrated to encode the viral hemagglutinin and determines reovirus cell tropism in the nervous system.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-1082140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-14440555,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-204941,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-210232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-233901,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-233918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-271999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-302303,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-302310,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-303568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-305464,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-306072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-306410,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-4309401,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-55454,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-566483,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-58463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-619493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-65141,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-664214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-794412,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-79615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-840296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-875135,
http://linkedlifedata.com/resource/pubmed/commentcorrection/218202-925604
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
442-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:218202-Animals,
pubmed-meshheading:218202-Cytotoxicity, Immunologic,
pubmed-meshheading:218202-Genes, MHC Class II,
pubmed-meshheading:218202-Genes, Viral,
pubmed-meshheading:218202-H-2 Antigens,
pubmed-meshheading:218202-Major Histocompatibility Complex,
pubmed-meshheading:218202-Mice,
pubmed-meshheading:218202-Reoviridae,
pubmed-meshheading:218202-Reoviridae Infections,
pubmed-meshheading:218202-T-Lymphocytes
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pubmed:year |
1979
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pubmed:articleTitle |
Generation of cytolytic T lymphocytes after reovirus infection: role of S1 gene.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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