Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-5-2
pubmed:abstractText
When the DNA-binding site for the Saccharomyces cerevisiae transcription activator GAL4 is placed upstream of the Schizosaccharomyces pombe ADH1 TATA box, transcription of the ADH1 gene is activated in S. pombe in vivo by an endogenous transcription factor. In vitro studies show that this S. pombe protein, PGA4, binds specifically to DNA containing a GAL4 site and that when two GAL4 sites are present, this protein binds cooperatively. Cooperating binding of PGA4 to DNA is favored if the GAL4 sites are separated by an integral number of turns of the DNA helix.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-2830022, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-2830478, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-2834068, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-2836064, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-2882858, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3028647, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3044608, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3079885, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3104772, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3124106, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3125422, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-3132708, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-4028160, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-6246368, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-6294096, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-6296690, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-6327053, http://linkedlifedata.com/resource/pubmed/commentcorrection/2181274-6433345
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0270-7306
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1432-8
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed-meshheading:2181274-Base Sequence, pubmed-meshheading:2181274-Cell Nucleus, pubmed-meshheading:2181274-DNA, Fungal, pubmed-meshheading:2181274-DNA-Binding Proteins, pubmed-meshheading:2181274-Fungal Proteins, pubmed-meshheading:2181274-Gene Expression Regulation, pubmed-meshheading:2181274-Genes, Fungal, pubmed-meshheading:2181274-Genetic Vectors, pubmed-meshheading:2181274-Molecular Sequence Data, pubmed-meshheading:2181274-Nucleic Acid Conformation, pubmed-meshheading:2181274-Oligonucleotide Probes, pubmed-meshheading:2181274-Promoter Regions, Genetic, pubmed-meshheading:2181274-Saccharomyces cerevisiae, pubmed-meshheading:2181274-Saccharomyces cerevisiae Proteins, pubmed-meshheading:2181274-Saccharomycetales, pubmed-meshheading:2181274-Schizosaccharomyces, pubmed-meshheading:2181274-Transcription Factors
pubmed:year
1990
pubmed:articleTitle
Identification of Schizosaccharomyces pombe transcription factor PGA4, which binds cooperatively to Saccharomyces cerevisiae GAL4-binding sites.
pubmed:affiliation
Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Massachusetts 02138.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.