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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2011-9-7
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pubmed:abstractText |
Colorectal cancer (CRC) is the second cause of cancer-related death in the Western world. Much of the CRC genetic risk remains unidentified and may be attributable to a large number of common, low-penetrance genetic variants. Genetic linkage studies in CRC families have reported additional association with regions 9q22-31, 3q21-24, 7q31, 11q, 14q and 22q. There are several plausible candidate genes for CRC susceptibility within the aforementioned linkage regions including PTCH1, XPA and TGFBR1 in 9q22-31, and EPHB1 and MRAS in 3q21-q24.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/GPI-Linked Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SEMA7A protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Semaphorins,
http://linkedlifedata.com/resource/pubmed/chemical/TOPBP1 protein, human
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1532-1827
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pubmed:author |
pubmed-author:AbulíAA,
pubmed-author:AndrewKK,
pubmed-author:ArgüelloLL,
pubmed-author:BessaXX,
pubmed-author:BujandaLL,
pubmed-author:CarracedoAA,
pubmed-author:CarreñoRR,
pubmed-author:Carvajal-CarmonaLL,
pubmed-author:CastellsAA,
pubmed-author:Castellví-BelSS,
pubmed-author:Fernández-RozadillaCC,
pubmed-author:GarcíaA MAM,
pubmed-author:Gastrointestinal Oncology Group of the Spanish Gastroenterological...,
pubmed-author:GiráldezM DMD,
pubmed-author:GonzaloVV,
pubmed-author:HoulstonR SRS,
pubmed-author:JoverRR,
pubmed-author:KerrD JDJ,
pubmed-author:LanasAA,
pubmed-author:LlorXX,
pubmed-author:MuñozJJ,
pubmed-author:PiquéJ MJM,
pubmed-author:ReñéJ MJM,
pubmed-author:Ruiz-PonteCC,
pubmed-author:SalóJJ,
pubmed-author:TomlinsonI P MIP,
pubmed-author:VilellaAA,
pubmed-author:XicolaR MRM
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pubmed:issnType |
Electronic
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pubmed:day |
6
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pubmed:volume |
105
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
870-5
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pubmed:meshHeading |
pubmed-meshheading:21811255-Aged,
pubmed-meshheading:21811255-Antigens, CD,
pubmed-meshheading:21811255-Carrier Proteins,
pubmed-meshheading:21811255-Case-Control Studies,
pubmed-meshheading:21811255-Chromosomes, Human, Pair 3,
pubmed-meshheading:21811255-Chromosomes, Human, Pair 9,
pubmed-meshheading:21811255-Colorectal Neoplasms,
pubmed-meshheading:21811255-DNA-Binding Proteins,
pubmed-meshheading:21811255-GPI-Linked Proteins,
pubmed-meshheading:21811255-Genetic Association Studies,
pubmed-meshheading:21811255-Genetic Predisposition to Disease,
pubmed-meshheading:21811255-Humans,
pubmed-meshheading:21811255-Male,
pubmed-meshheading:21811255-Nuclear Proteins,
pubmed-meshheading:21811255-Polymorphism, Single Nucleotide,
pubmed-meshheading:21811255-Semaphorins
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pubmed:year |
2011
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pubmed:articleTitle |
A two-phase case-control study for colorectal cancer genetic susceptibility: candidate genes from chromosomal regions 9q22 and 3q22.
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pubmed:affiliation |
Department of Gastroenterology, Hospital Clínic, CIBERehd, IDIBAPS, University of Barcelona, Villarroel 170, 08036, Barcelona, Catalonia, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study
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