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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2011-9-2
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pubmed:abstractText |
Diffusion tensor imaging (DTI) measures the random motion of water molecules reflecting central nervous system tissue integrity and pathology. Glaucoma damages retinal ganglion cells (RGCs) and their axons. The authors hypothesized that DTI-derived axonal and myelin injury biomarkers may be used to detect early axonal damage and may be correlated with RGC loss in the mouse model of optic nerve crush (ONC).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7001-6
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pubmed:meshHeading |
pubmed-meshheading:21810979-Animals,
pubmed-meshheading:21810979-Axons,
pubmed-meshheading:21810979-Biological Markers,
pubmed-meshheading:21810979-Cell Count,
pubmed-meshheading:21810979-Diffusion Tensor Imaging,
pubmed-meshheading:21810979-Disease Models, Animal,
pubmed-meshheading:21810979-Female,
pubmed-meshheading:21810979-Mice,
pubmed-meshheading:21810979-Mice, Inbred C57BL,
pubmed-meshheading:21810979-Myelin Basic Proteins,
pubmed-meshheading:21810979-Nerve Crush,
pubmed-meshheading:21810979-Nerve Degeneration,
pubmed-meshheading:21810979-Neurofilament Proteins,
pubmed-meshheading:21810979-Optic Nerve Diseases,
pubmed-meshheading:21810979-Retinal Ganglion Cells,
pubmed-meshheading:21810979-Stilbamidines
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pubmed:year |
2011
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pubmed:articleTitle |
Diffusion tensor imaging detects retinal ganglion cell axon damage in the mouse model of optic nerve crush.
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pubmed:affiliation |
Department of Radiology, Washington University, St. Louis, Missouri, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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