21804938

Source:http://linkedlifedata.com/resource/pubmed/id/21804938

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0018213, umls-concept:C0237401, umls-concept:C0439662, umls-concept:C0887947, umls-concept:C1280464, umls-concept:C1704686
pubmed:dateCreated	2011-8-1
pubmed:abstractText	Graves' disease after the initiation of highly active antiretroviral therapy (HAART) in certain HIV-1-infected individuals has been described as an immune reconstitution inflammatory syndrome (IRIS). This phenomenon should be suspected in individuals who present with clinical deterioration and a presentation suggestive of hyperthyroidism despite good virological and immunological response to HAART. Signs and symptoms of hyperthyroidism may be discrete or overt and typically develop 8-33 months after initiating therapy. One to two percent of HIV-infected patients can present with overt thyroid disease. Relatively few cases of Graves' IRIS have been reported in the literature to date. We describe four cases of Graves' IRIS in HIV-infected patients who were started on HAART therapy.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-11095463, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-15018703, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-15650365, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-15758839, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-16439886, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-16449004, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-16553555, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-17638201, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-19092451, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-20413021, http://linkedlifedata.com/resource/pubmed/commentcorrection/21804938-9516219
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101553816
pubmed:status	PubMed-not-MEDLINE
pubmed:issn	2090-1259
pubmed:author	pubmed-author:DelapenhaRobertR, pubmed-author:FarhatFariaF, pubmed-author:GajjalaJhansiJ, pubmed-author:RasulSamadS, pubmed-author:ZahraSyeda MehreenSM
pubmed:issnType	Electronic
pubmed:volume	2011
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	743597
pubmed:year	2011
pubmed:articleTitle	Graves' Disease as a Manifestation of Immune Reconstitution in HIV-Infected Individuals after Initiation of Highly Active Antiretroviral Therapy.
pubmed:affiliation	Division of Infectious Diseases, Department of Internal Medicine, Howard University Hospital, Washington DC, USA.
pubmed:publicationType	Journal Article