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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1979-5-16
|
pubmed:abstractText |
Of ninety-one subcultured foci of SV40-transformed WI-38 human diploid fibroblasts, none yielded cells that grew indefinitely, but all cells in each subculture continued to produce T antigen and to look morphologically transformed throughout their lifespan. These results are consistent with the commitment theory of fibroblast senescence, but predict that a special transformation event is necessary to accout for the rare survivors.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
409-14
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:217965-Antigens, Neoplasm,
pubmed-meshheading:217965-Antigens, Viral,
pubmed-meshheading:217965-Cell Division,
pubmed-meshheading:217965-Cell Line,
pubmed-meshheading:217965-Cell Survival,
pubmed-meshheading:217965-Cell Transformation, Neoplastic,
pubmed-meshheading:217965-Cell Transformation, Viral,
pubmed-meshheading:217965-Humans,
pubmed-meshheading:217965-Lung,
pubmed-meshheading:217965-Simian virus 40
|
pubmed:year |
1979
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pubmed:articleTitle |
SV40-transformed human diploid cells that remain transformed throughout their limited lifespan.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|