Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1979-5-16
|
pubmed:abstractText |
The induction of a type C virus from a strain of human embryonic lung cells (HEL-12) by iododeoxyuridine (IdUrd) was examined at various times during in vitro propagation. IdUrd did not elicit type C virus production immediately following initiation of cultures from frozen primary HEL-12 cells. After overnight treatment with 30 microgram/ml IdUrd the cells expressed viral antigens and produced a type C virus between the 25th and 80th day of in vitro growth. Production of the induced type C virus was transient. Single-cell clones of the parental HEL-12 strain were likewise susceptible to type C virus production by IdUrd. The ability of IdUrd to induce virus terminated with the onset of spontaneous type C virus production from HEL-12 cells at between 80 and 120 days of in vitro growth.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0022-1317
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
42
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
399-403
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:217963-Antigens, Viral,
pubmed-meshheading:217963-Cell Line,
pubmed-meshheading:217963-Clone Cells,
pubmed-meshheading:217963-Humans,
pubmed-meshheading:217963-Idoxuridine,
pubmed-meshheading:217963-Lung,
pubmed-meshheading:217963-Retroviridae,
pubmed-meshheading:217963-Virus Replication
|
pubmed:year |
1979
|
pubmed:articleTitle |
Type C virus induced by iododeoxyuridine in the human embryonic cell strain HEL-12.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|