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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2011-8-25
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pubmed:abstractText |
A large outbreak of diarrhea and the hemolytic-uremic syndrome caused by an unusual serotype of Shiga-toxin-producing Escherichia coli (O104:H4) began in Germany in May 2011. As of July 22, a large number of cases of diarrhea caused by Shiga-toxin-producing E. coli have been reported--3167 without the hemolytic-uremic syndrome (16 deaths) and 908 with the hemolytic-uremic syndrome (34 deaths)--indicating that this strain is notably more virulent than most of the Shiga-toxin-producing E. coli strains. Preliminary genetic characterization of the outbreak strain suggested that, unlike most of these strains, it should be classified within the enteroaggregative pathotype of E. coli.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1533-4406
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pubmed:author |
pubmed-author:BashirAliA,
pubmed-author:BoisenNadiaN,
pubmed-author:BullardJamesJ,
pubmed-author:ChinChen-ShanCS,
pubmed-author:EidJohnJ,
pubmed-author:Frimodt-MøllerJakobJ,
pubmed-author:IliopoulosDimitrisD,
pubmed-author:KasarskisAndrewA,
pubmed-author:KislyukAndrey OAO,
pubmed-author:KlammerAaronA,
pubmed-author:KrogfeltKaren AKA,
pubmed-author:LeeLawrenceL,
pubmed-author:NataroJames PJP,
pubmed-author:PaxinosEllen EEE,
pubmed-author:PelusoPaulP,
pubmed-author:PetersenAndreas MAM,
pubmed-author:RankDavidD,
pubmed-author:RaskoDavid ADA,
pubmed-author:RedmanJulia CJC,
pubmed-author:SahlJason WJW,
pubmed-author:SchadtEric EEE,
pubmed-author:ScheutzFlemmingF,
pubmed-author:SebraRobertR,
pubmed-author:SteyertSusan RSR,
pubmed-author:StruveCarstenC,
pubmed-author:WaldorMatthew KMK,
pubmed-author:WangSusannaS,
pubmed-author:WebsterDale RDR
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pubmed:issnType |
Electronic
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pubmed:day |
25
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pubmed:volume |
365
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
709-17
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
pubmed-meshheading:21793740-Bacterial Typing Techniques,
pubmed-meshheading:21793740-Base Sequence,
pubmed-meshheading:21793740-Diarrhea,
pubmed-meshheading:21793740-Disease Outbreaks,
pubmed-meshheading:21793740-Escherichia coli Infections,
pubmed-meshheading:21793740-Feces,
pubmed-meshheading:21793740-Female,
pubmed-meshheading:21793740-Genome, Bacterial,
pubmed-meshheading:21793740-Germany,
pubmed-meshheading:21793740-Hemolytic-Uremic Syndrome,
pubmed-meshheading:21793740-Humans,
pubmed-meshheading:21793740-Middle Aged,
pubmed-meshheading:21793740-Phylogeny,
pubmed-meshheading:21793740-Polymerase Chain Reaction,
pubmed-meshheading:21793740-Sequence Analysis, DNA,
pubmed-meshheading:21793740-Shiga-Toxigenic Escherichia coli
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pubmed:year |
2011
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pubmed:articleTitle |
Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany.
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pubmed:affiliation |
University of Maryland School of Medicine, Institute for Genome Sciences and Department of Microbiology, Baltimore, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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