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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2011-9-21
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pubmed:abstractText |
There is a known association of imbalanced peripheral tolerance and autoimmune diseases. The binding of programmed cell death 1 (PD-1) with its ligands 1 and 2 (PD-L1 and PD-L2) inhibits T-cell proliferation through a negative signal via recruitment of src homology 2-domain-containing tyrosine phosphatase 2. Therefore we evaluated the effect of the PD-1, PD-L1 and PD-L2 genotypes on the occurrence of AS in a population of Taiwanese patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD274,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/CD274 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PCD1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/PDCD1LG2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Programmed Cell Death 1 Ligand 2...,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1462-0332
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1809-13
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21791547-Adult,
pubmed-meshheading:21791547-Antigens, CD,
pubmed-meshheading:21791547-Antigens, CD274,
pubmed-meshheading:21791547-Antigens, CD80,
pubmed-meshheading:21791547-Female,
pubmed-meshheading:21791547-Genetic Predisposition to Disease,
pubmed-meshheading:21791547-Genotype,
pubmed-meshheading:21791547-Humans,
pubmed-meshheading:21791547-Male,
pubmed-meshheading:21791547-Middle Aged,
pubmed-meshheading:21791547-Neoplasm Proteins,
pubmed-meshheading:21791547-Polymerase Chain Reaction,
pubmed-meshheading:21791547-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:21791547-Polymorphism, Single Nucleotide,
pubmed-meshheading:21791547-Programmed Cell Death 1 Ligand 2 Protein,
pubmed-meshheading:21791547-Risk Factors,
pubmed-meshheading:21791547-Spondylitis, Ankylosing,
pubmed-meshheading:21791547-Transcription Factors
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pubmed:year |
2011
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pubmed:articleTitle |
Effects of genetic polymorphisms of programmed cell death 1 and its ligands on the development of ankylosing spondylitis.
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pubmed:affiliation |
1Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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