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Predicate | Object |
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rdf:type | |
lifeskim:mentions |
umls-concept:C0023542,
umls-concept:C0023607,
umls-concept:C0023610,
umls-concept:C0030685,
umls-concept:C0032016,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0229535,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1533691,
umls-concept:C1705241,
umls-concept:C1705242,
umls-concept:C1948023,
umls-concept:C1963578
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pubmed:issue |
3
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pubmed:dateCreated |
1990-4-26
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pubmed:abstractText |
Continuous administration of leukotriene C4 (LTC4, 10(-10) M) to superfused rat anterior pituitary cells increased LH release for 40 min only, whereas in a parallel experiment gonadotropin-releasing hormone (GnRH, 10(-9) M) evoked a continuous increase in hormone secretion. In contrast to GnRH, LTC4 did not desensitize rat anterior pituitary cells. The secretory action resulting from the administration of LTC4 (10(-10) M) was abolished for 40 min after previous stimulation. The results documented the dual action of LTC4 on LH exocytosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0014-4754
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
298-300
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2178956-Animals,
pubmed-meshheading:2178956-Cells, Cultured,
pubmed-meshheading:2178956-Luteinizing Hormone,
pubmed-meshheading:2178956-Pituitary Gland, Anterior,
pubmed-meshheading:2178956-Pituitary Hormone-Releasing Hormones,
pubmed-meshheading:2178956-Rats,
pubmed-meshheading:2178956-SRS-A,
pubmed-meshheading:2178956-Stimulation, Chemical
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pubmed:year |
1990
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pubmed:articleTitle |
Differences in luteinizing hormone release stimulated in rat anterior pituitary cells by leukotriene C4 and by gonadotropin-releasing hormone in vitro.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Division of Gynecological Endocrinology, Heidelberg, Federal Republic of Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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