Linked Life Data

21780251

Source:http://linkedlifedata.com/resource/pubmed/id/21780251

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-7-22
pubmed:abstractText
An interesting clinical option for optimizing healing tissue is the use of platelet concentrate. Platelets contain high quantities of growth factors, among these TGF-?1 and VEGF, which are known to be implicated in tissue regeneration. CGF is produced by processing blood samples with a special centrifuge device; three layers are formed: top acellular plasma (PPP), middle CGF and bottom red blood cells (RBC) layers. Given that to date there are no data concerning the biological characteristic of CGF, the aim of this study was to evaluate the presence of TGF-?1 and VEGF in CGF and also in PPP and RBC layers. In addition, since circulating stem cells are recruited from blood to injured tissue for healing we also evaluated the presence of CD34 positive cells. Our data show the presence of TGF-?1 and VEGF in CGF and RBC layers. In addition, we show CD34 positive cells in CGF.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1097-0029
pubmed:author
pubmed:copyrightInfo
Copyright © 2010 Wiley-Liss, Inc.
pubmed:issnType
Electronic
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
772-7
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction.
pubmed:affiliation
Department of Biomedical Sciences and Biotechnologies, Division of Human Anatomy, University of Brescia, V.le Europa 11, 25123 Brescia, Italy. rodella@med.unibs.it
pubmed:publicationType
Journal Article