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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
1991-3-12
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pubmed:abstractText |
Fourty patients who underwent general surgery have been enrolled in a double-blind controlled trial which evaluated the efficacy and safety of Fragmin, a new low molecular weight heparin, chosen to be the 1st OMS International Standard for LMWH. Fragmin 2500 UI anti-Xa once daily and unfractionated heparin 5000 UI twice daily were administered to prevent postoperative deep venous thrombosis. Prophylaxis began two hours before surgery and continued for the next 5 postoperative days. The incidence of isotopic venous thrombosis, thromboembolic disorders and bleeding complications have been evaluated. Results have shown a similar efficacy and safety profile of the two drugs, although Fragmin doses are markedly inferior to unfractionated heparin's. Moreover, Fragmin has the advantage of a single daily administration, with a better patients' compliance and an easier and less expensive nursing care.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
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pubmed:issn |
0026-4733
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1101-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2177861-Adult,
pubmed-meshheading:2177861-Double-Blind Method,
pubmed-meshheading:2177861-Heparin,
pubmed-meshheading:2177861-Heparin, Low-Molecular-Weight,
pubmed-meshheading:2177861-Humans,
pubmed-meshheading:2177861-Male,
pubmed-meshheading:2177861-Postoperative Care,
pubmed-meshheading:2177861-Preoperative Care,
pubmed-meshheading:2177861-Risk Factors,
pubmed-meshheading:2177861-Thrombophlebitis
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pubmed:year |
1990
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pubmed:articleTitle |
[Evaluation of the effectiveness and safety of Fragmin (Kabi 2165) versus calcium heparin in the prevention of deep venous thrombosis in general surgery].
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pubmed:affiliation |
I Divisione Chirurgica, Ospedale Fatebenefratelli e Oftalmico (FBF), Milano.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract,
Randomized Controlled Trial
|