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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-3-8
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pubmed:abstractText |
Clonal karyotypic abnormalities were detected in 7 of 42 cytogenetically analyzed benign ovarian tumors. An adenofibroma had -X and a mucinous cystadenoma had t(1;11)(q25;q23) as the sole abnormality. Trisomy 12 was found in the remaining five tumors. It was the only change in two fibromas and a serous cystadenoma; the fourth tumor, a mucinous cystadenoma, had one clone with +12 and one with +12 and +10, and the fifth tumor, a fibrothecoma, had +4,+9,+12. The finding of trisomy 12 in five of seven karyotypically aberrant tumors suggests that this aberration characterizes a hitherto unrecognized cytogenetic subgroup of benign ovarian neoplasms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1045-2257
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:geneSymbol |
KRAS
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
48-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2177641-Adenofibroma,
pubmed-meshheading:2177641-Chromosomes, Human, Pair 12,
pubmed-meshheading:2177641-Clone Cells,
pubmed-meshheading:2177641-Cystadenoma,
pubmed-meshheading:2177641-Female,
pubmed-meshheading:2177641-Fibroma,
pubmed-meshheading:2177641-Humans,
pubmed-meshheading:2177641-Ovarian Neoplasms,
pubmed-meshheading:2177641-Thecoma,
pubmed-meshheading:2177641-Trisomy
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pubmed:year |
1990
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pubmed:articleTitle |
Trisomy 12 is a consistent chromosomal aberration in benign ovarian tumors.
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pubmed:affiliation |
Department of Clinical Genetics, University Hospital, Lund, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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