Linked Life Data

21772280

Source:http://linkedlifedata.com/resource/pubmed/id/21772280

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2011-7-20
pubmed:abstractText
Inflammation is a fundamental protective response that sometimes goes awry and becomes a major cofactor in the pathogenesis of many chronic human diseases, including cancer. Here we review the evolutionary relationship and opposing functions of the transcription factor NF-?B in inflammation and cancer. Although it seems to fulfill a distinctly tumor-promoting role in many types of cancer, NF-?B has a confounding role in certain tumors. Understanding the activity and function of NF-?B in the context of tumorigenesis is critical for its successful taming, an important challenge for modern cancer biology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1529-2916
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
715-23
pubmed:dateRevised
2011-10-27
pubmed:meshHeading
pubmed:year
2011
pubmed:articleTitle
Inflammation meets cancer, with NF-?B as the matchmaker.
pubmed:affiliation
Lautenberg Center for Immunology, Institute for Medical Research-Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel. yinon@cc.huji.ac.il
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't