| pubmed-article:21768025 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0011923 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0729936 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0011209 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0547070 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C1442080 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:21768025 | lifeskim:mentions | umls-concept:C1522207 | lld:lifeskim |
| pubmed-article:21768025 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:21768025 | pubmed:dateCreated | 2011-7-19 | lld:pubmed |
| pubmed-article:21768025 | pubmed:abstractText | A method is introduced to monitor cardiac ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound variations with temperature. The sound speed of water-bearing tissue such as cardiac muscle increases with temperature. However, at temperatures above about 50°C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48 to 50°C for a short period in accordance with the well-known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs by using the reduced slope in the thermal strain curve as a function of heating time. We have illustrated the feasibility of this method initially using porcine myocardium in vitro. The method was further demonstrated in vivo, using a specially equipped ablation tip and an 11-MHz microlinear intracardiac echocardiography (ICE) array mounted on the tip of a catheter. The thermal strain curves showed a plateau, strongly suggesting that the temperature reached at least 50°C. | lld:pubmed |
| pubmed-article:21768025 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21768025 | pubmed:language | eng | lld:pubmed |
| pubmed-article:21768025 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:21768025 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:21768025 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:21768025 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:21768025 | pubmed:issn | 1525-8955 | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:DedeKK | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:SahnDavid JDJ | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:O'DonnellMatt... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:ChenPeterP | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:ShivkumarKaly... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:TruongUyenU | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:MahajanAmanA | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:OralkanOmerO | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:StephensDougl... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:NikoozadehAmi... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:ThoNguyenN | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:CannataJonath... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:ThomeniusKai... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:ParkSuhyunS | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:DentingerAaro... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:WildesDouglas... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:SeoChi... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:JeongJong... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:de La... | lld:pubmed |
| pubmed-article:21768025 | pubmed:author | pubmed-author:Khuri-YakubPi... | lld:pubmed |
| pubmed-article:21768025 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:21768025 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:21768025 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:21768025 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:21768025 | pubmed:pagination | 1406-17 | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:meshHeading | pubmed-meshheading:21768025... | lld:pubmed |
| pubmed-article:21768025 | pubmed:year | 2011 | lld:pubmed |
| pubmed-article:21768025 | pubmed:articleTitle | The feasibility of using thermal strain imaging to regulate energy delivery during intracardiac radio-frequency ablation. | lld:pubmed |
| pubmed-article:21768025 | pubmed:affiliation | University of California, Davis, Department of Biomedical Engineering, Davis, CA, USA. | lld:pubmed |
| pubmed-article:21768025 | pubmed:publicationType | Journal Article | lld:pubmed |
