Source:http://linkedlifedata.com/resource/pubmed/id/21768025
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
2011-7-19
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| pubmed:abstractText |
A method is introduced to monitor cardiac ablative therapy by examining slope changes in the thermal strain curve caused by speed of sound variations with temperature. The sound speed of water-bearing tissue such as cardiac muscle increases with temperature. However, at temperatures above about 50°C, there is no further increase in the sound speed and the temperature coefficient may become slightly negative. For ablation therapy, an irreversible injury to tissue and a complete heart block occurs in the range of 48 to 50°C for a short period in accordance with the well-known Arrhenius equation. Using these two properties, we propose a potential tool to detect the moment when tissue damage occurs by using the reduced slope in the thermal strain curve as a function of heating time. We have illustrated the feasibility of this method initially using porcine myocardium in vitro. The method was further demonstrated in vivo, using a specially equipped ablation tip and an 11-MHz microlinear intracardiac echocardiography (ICE) array mounted on the tip of a catheter. The thermal strain curves showed a plateau, strongly suggesting that the temperature reached at least 50°C.
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| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
|
| pubmed:issn |
1525-8955
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| pubmed:author |
pubmed-author:CannataJonathanJ,
pubmed-author:ChenPeterP,
pubmed-author:DedeKK,
pubmed-author:DentingerAaronA,
pubmed-author:JeongJong SeobJS,
pubmed-author:Khuri-YakubPierre TPT,
pubmed-author:MahajanAmanA,
pubmed-author:NikoozadehAminA,
pubmed-author:O'DonnellMatthewM,
pubmed-author:OralkanOmerO,
pubmed-author:ParkSuhyunS,
pubmed-author:SahnDavid JDJ,
pubmed-author:SeoChi HyungCH,
pubmed-author:ShivkumarKalyanamK,
pubmed-author:StephensDouglas NDN,
pubmed-author:ThoNguyenN,
pubmed-author:ThomeniusKai EKE,
pubmed-author:TruongUyenU,
pubmed-author:WildesDouglasD,
pubmed-author:de La RamaAlanA
|
| pubmed:issnType |
Electronic
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| pubmed:volume |
58
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1406-17
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| pubmed:meshHeading |
pubmed-meshheading:21768025-Animals,
pubmed-meshheading:21768025-Cardiac Surgical Procedures,
pubmed-meshheading:21768025-Catheter Ablation,
pubmed-meshheading:21768025-Echocardiography,
pubmed-meshheading:21768025-Feasibility Studies,
pubmed-meshheading:21768025-Hot Temperature,
pubmed-meshheading:21768025-Intraoperative Complications,
pubmed-meshheading:21768025-Myocardium,
pubmed-meshheading:21768025-Signal Processing, Computer-Assisted,
pubmed-meshheading:21768025-Swine
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| pubmed:year |
2011
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| pubmed:articleTitle |
The feasibility of using thermal strain imaging to regulate energy delivery during intracardiac radio-frequency ablation.
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| pubmed:affiliation |
University of California, Davis, Department of Biomedical Engineering, Davis, CA, USA.
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| pubmed:publicationType |
Journal Article
|