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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1991-2-19
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pubmed:abstractText |
Mouse vasopressin (VP) and oxytocin (OT) genes were isolated from a genomic library and the nucleotide sequences of the two genes were determined. The two genes have similar three exon structures and a high similarity in the part of exon 1 encoding vasopressin or oxytocin nonapeptide and in exon 2 encoding the central core of neurophysin. They are linked together in a tail to tail orientation separated by a short 3.5 kb intergenic sequence and are transcribed from opposite strands. Both genes have a single transcription initiation site downstream from a TATA-like sequence and a single polyadenylated transcript of about 760 bp for the vasopressin mRNA and about 700 bp for the oxytocin mRNA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0169-328X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
319-24
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2176709-Amino Acid Sequence,
pubmed-meshheading:2176709-Animals,
pubmed-meshheading:2176709-Base Sequence,
pubmed-meshheading:2176709-Cloning, Molecular,
pubmed-meshheading:2176709-Genetic Linkage,
pubmed-meshheading:2176709-Immunoblotting,
pubmed-meshheading:2176709-Mice,
pubmed-meshheading:2176709-Molecular Sequence Data,
pubmed-meshheading:2176709-Oligonucleotide Probes,
pubmed-meshheading:2176709-Oxytocin,
pubmed-meshheading:2176709-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2176709-Single-Strand Specific DNA and RNA Endonucleases,
pubmed-meshheading:2176709-Species Specificity,
pubmed-meshheading:2176709-Vasopressins
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pubmed:year |
1990
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pubmed:articleTitle |
Structure of mouse vasopressin and oxytocin genes.
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pubmed:affiliation |
Laboratory of Neurochemistry, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article
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