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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11-12
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pubmed:dateCreated |
2011-8-22
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pubmed:abstractText |
Advanced glycation end products (AGEs) are produced by glycoxidation and lipid peroxidation. AGEs induce oxidative stress and inflammation, and accumulate in tubular cells after kidney transplantation. We hypothesize that the AGE formation blocker aminoguanidine (AG) reduces AGE formation and improves renal transplant function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/8-epi-prostaglandin F2alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Benzimidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiotonic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Dinoprost,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Glycosylation End Products, Advanced,
http://linkedlifedata.com/resource/pubmed/chemical/Guanidines,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyproline,
http://linkedlifedata.com/resource/pubmed/chemical/Lysine,
http://linkedlifedata.com/resource/pubmed/chemical/N(6)-carboxymethyllysine,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrazoles,
http://linkedlifedata.com/resource/pubmed/chemical/candesartan,
http://linkedlifedata.com/resource/pubmed/chemical/pimagedine
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2011 Elsevier Inc. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:day |
12
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
349-54
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pubmed:meshHeading |
pubmed-meshheading:21763321-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:21763321-Animals,
pubmed-meshheading:21763321-Benzimidazoles,
pubmed-meshheading:21763321-Cardiotonic Agents,
pubmed-meshheading:21763321-Dinoprost,
pubmed-meshheading:21763321-Enzyme Inhibitors,
pubmed-meshheading:21763321-Glycosylation End Products, Advanced,
pubmed-meshheading:21763321-Guanidines,
pubmed-meshheading:21763321-Hydroxyproline,
pubmed-meshheading:21763321-Kidney Diseases,
pubmed-meshheading:21763321-Kidney Function Tests,
pubmed-meshheading:21763321-Kidney Transplantation,
pubmed-meshheading:21763321-Lysine,
pubmed-meshheading:21763321-Male,
pubmed-meshheading:21763321-Oxidative Stress,
pubmed-meshheading:21763321-Proteinuria,
pubmed-meshheading:21763321-Rats,
pubmed-meshheading:21763321-Rats, Inbred F344,
pubmed-meshheading:21763321-Rats, Inbred Lew,
pubmed-meshheading:21763321-Tetrazoles,
pubmed-meshheading:21763321-Time Factors,
pubmed-meshheading:21763321-Transplantation, Homologous
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pubmed:year |
2011
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pubmed:articleTitle |
AGE formation blockade with aminoguanidine does not ameliorate chronic allograft nephropathy.
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pubmed:affiliation |
Department of Nephrology, Klinikum rechts der Isar, Technical University Munich, Germany. christoph.schmaderer@lrz.tum.de
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pubmed:publicationType |
Journal Article,
Comparative Study
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