Linked Life Data

2175468

Source:http://linkedlifedata.com/resource/pubmed/id/2175468

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1991-1-31
pubmed:abstractText
Results obtained from cytological and immunological analysis of FLK 44/2 cells indicate the transformation and heterogenization of BLV-producing cell culture. Karyotypic changes of the culture were observed, as well as alterations in its antigenic specificity leading to antigenic diversion. The cell population displayed a high proliferation activity limited by topoinhibition and culture medium exhaustion. An immunocytochemical investigation of virus-producing cell population, using monoclonal and polyclonal antibodies against BLV revealed various cellular forms of BLV-expression. A possibility is discussed to use the immunological approach for selection and establishment of cellular clones exhibiting appropriate virus production parameters.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0041-3771
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
728-35
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[The cytological and immunological characteristics of a virus-producing FLK 44/2 culture].
pubmed:publicationType
Journal Article, English Abstract