Linked Life Data

21747584

Source:http://linkedlifedata.com/resource/pubmed/id/21747584

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-7-12
pubmed:abstractText
THERE ARE TWO MAJOR CLASSES OF GENETIC ASSOCIATION ANALYSES: population based and family based. Population-based case-control studies have been the method of choice due to the ease of data collection. However, population stratification is one of the major limitations of case-control studies, while family-based studies are protected against stratification. In this study, we carry out extensive simulations under different disease models (both Mendelian as well as complex) to evaluate the relative powers of the two approaches in detecting association.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
May
pubmed:issn
0971-6866
pubmed:author
pubmed:issnType
Print
pubmed:volume
17 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S27-31
pubmed:dateRevised
2011-8-1
pubmed:year
2011
pubmed:articleTitle
Power comparison between population-based case-control studies and family-based transmission-disequilibrium tests: An empirical study.
pubmed:affiliation
Human Genetics Unit, Indian Statistical Institute, Kolkata, West Bengal, India.
pubmed:publicationType
Journal Article