Linked Life Data

2174566

Source:http://linkedlifedata.com/resource/pubmed/id/2174566

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-1-15
pubmed:abstractText
While prostaglandins of the E series are known to affect several small intestinal functions, their cellular mechanisms are poorly understood. The purposes of this study were to determine if there are developmental differences in the binding of PGE1, to the small intestinal enterocyte and if this binding may be affected by glucocorticoids, which are known to accelerate maturation of the small intestine. Small intestinal binding of prostaglandin E1 was significantly higher in adult rats when compared to postweaned (25-day-old) and preweaned (15- to 17-day-old) rats. Hydrocortisone administration for two days had no effect on the binding of prostaglandin E1 in either preweaned of adult rats. We conclude that a developmental change occurs in prostaglandin E1 binding to the plasma membrane of the rat small intestinal enterocyte during maturation. This binding is not affected by the administration of hydrocortisone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0952-3278
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Ontogeny of prostaglandin E1 receptor binding in rat small intestine.
pubmed:affiliation
Department of Pediatrics, University of Florida College of Medicine, Gainesville 32610.
pubmed:publicationType
Journal Article, Comparative Study