Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2011-8-10
pubmed:abstractText
Two clinical isolates of Escherichia coli, EC18 and EC21, were non-susceptible (MICs 4-16 mg/L) to cefpirome and cefepime, with marked synergy with clavulanate, yet were susceptible to cefotaxime and ceftazidime (MICs ? 1 mg/L). EC19, from the same patient as EC21, was susceptible to all four cephalosporins. We sought to characterize the molecular basis of resistance in isolates EC18 and EC21.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Outer Membrane Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Cephalosporins, http://linkedlifedata.com/resource/pubmed/chemical/Clavulanic Acid, http://linkedlifedata.com/resource/pubmed/chemical/DNA, http://linkedlifedata.com/resource/pubmed/chemical/DNA, Recombinant, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/OmpC protein, http://linkedlifedata.com/resource/pubmed/chemical/OmpF protein, http://linkedlifedata.com/resource/pubmed/chemical/Porins, http://linkedlifedata.com/resource/pubmed/chemical/beta-Lactamases, http://linkedlifedata.com/resource/pubmed/chemical/beta-lactamase OXA-2, http://linkedlifedata.com/resource/pubmed/chemical/beta-lactamase TEM-1, http://linkedlifedata.com/resource/pubmed/chemical/cefepime, http://linkedlifedata.com/resource/pubmed/chemical/cefpirome
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1460-2091
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
66
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2006-10
pubmed:meshHeading
pubmed-meshheading:21742679-Anti-Bacterial Agents, pubmed-meshheading:21742679-Bacterial Outer Membrane Proteins, pubmed-meshheading:21742679-Cephalosporins, pubmed-meshheading:21742679-Clavulanic Acid, pubmed-meshheading:21742679-DNA, pubmed-meshheading:21742679-DNA, Recombinant, pubmed-meshheading:21742679-Drug Resistance, Bacterial, pubmed-meshheading:21742679-Electrophoresis, Gel, Pulsed-Field, pubmed-meshheading:21742679-Enzyme Inhibitors, pubmed-meshheading:21742679-Escherichia coli, pubmed-meshheading:21742679-Escherichia coli Infections, pubmed-meshheading:21742679-Isoelectric Focusing, pubmed-meshheading:21742679-Microbial Sensitivity Tests, pubmed-meshheading:21742679-Plasmids, pubmed-meshheading:21742679-Porins, pubmed-meshheading:21742679-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:21742679-Spectrometry, Mass, Matrix-Assisted Laser..., pubmed-meshheading:21742679-Transformation, Bacterial, pubmed-meshheading:21742679-beta-Lactamases
pubmed:year
2011
pubmed:articleTitle
False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.
pubmed:affiliation
Health Protection Agency, Microbiology Services-Colindale, London, UK. alejandro.beceiro.casas@sergas.es
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't