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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1991-1-8
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pubmed:abstractText |
The purpose of this study was to determine the extent of the relatedness between feline herpesvirus-1 (FHV-1) and canine herpesvirus (CHV). Immunoprecipitation studies using antisera to FHV-1 and CHV revealed that both share virion glycoprotein antigens with apparent molecular weights of approximately 60 and 68 kDa. Two non-glycosylated, virion-associated antigens of each virus also displayed weaker cross reactivity. Southern blot hybridization experiments indicated that restriction fragments which represented approximately 51% of the FHV-1 genome hybridized to CHV DNA under conditions which allowed less than 7% base pair mismatch. This is the first molecular characterization of cross-reactivity between FHV-1 and another herpesvirus.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0304-8608
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-45
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2174232-Animals,
pubmed-meshheading:2174232-Antigens, Viral,
pubmed-meshheading:2174232-Blotting, Southern,
pubmed-meshheading:2174232-Cat Diseases,
pubmed-meshheading:2174232-Cats,
pubmed-meshheading:2174232-Cross Reactions,
pubmed-meshheading:2174232-DNA, Viral,
pubmed-meshheading:2174232-Dog Diseases,
pubmed-meshheading:2174232-Dogs,
pubmed-meshheading:2174232-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:2174232-Herpesviridae,
pubmed-meshheading:2174232-Herpesviridae Infections,
pubmed-meshheading:2174232-Herpesvirus 1, Canid,
pubmed-meshheading:2174232-Nucleic Acid Hybridization,
pubmed-meshheading:2174232-Restriction Mapping,
pubmed-meshheading:2174232-Sequence Homology, Nucleic Acid
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pubmed:year |
1990
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pubmed:articleTitle |
Homology between feline herpesvirus-1 and canine herpesvirus.
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pubmed:affiliation |
Department of Microbiology and Public Health, Michigan State University, East Lansing.
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pubmed:publicationType |
Journal Article
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