Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1990-12-31
pubmed:abstractText
Healthy adult cocks were administered through the intramuscular route with 1 or 15 mg cyproterone acetate (CyA)/kg b. wt. or testosterone at the rate of 1.5 mg/kg b. wt. daily for a period of 25 days. High doses of CyA and testosterone caused severe suppression (P less than 0.01) of semen volume, sperm concentration, sperm motility and angiotensin converting enzyme activity (ACE EC 3.4.15.1). Fertilizing ability of spermatozoa was also reduced drastically at the end of treatment period. No loss of sexual behaviour was observed in treated birds as compared to controls. Recovery in all parameters from deleterious effects of these drugs was rapid after cessation of treatment. Lower doses of CyA did not affect the parameters of semen. The results are discussed in relation to the possible mechanism of action of CyA and testosterone.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0514-7158
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
499-505
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Effects of cyproterone acetate and testosterone treatments on some physical parameters, angiotensin converting enzyme activity and fertilizing ability of spermatozoa of domestic cocks (Gallus domesticus).
pubmed:affiliation
Division of Physiology and Reproduction, Central Avian Research Institute, Izatnagar, India.
pubmed:publicationType
Journal Article