Linked Life Data

21738521

Source:http://linkedlifedata.com/resource/pubmed/id/21738521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2011-7-8
pubmed:abstractText
Pin 1 is an enzyme that specifically catalyzes the cis-trans isomerization of phosphorylated serine/threonine-proline (pSer/Thr-Pro) motif in its substrate proteins. Recent studies demonstrate that stability of several viral proteins is regulated by phosphorylation-dependent prolyl-isomerization by a host factor Pin1. Pin1 is now positioned as an important modulator of the molecular crosstalk between virus and host cells and could be a unique target for anti-virus therapy. This new type of post-translational modification by Pin1 might be involved in the regulation of other viral proteins.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1664-302X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
107
pubmed:dateRevised
2011-8-1
pubmed:year
2010
pubmed:articleTitle
Pinning down viral proteins: a new prototype for virus-host cell interaction.
pubmed:affiliation
Department of Microbiology, Yokohama City University School of Medicine Yokohama, Kanagawa, Japan.
pubmed:publicationType
Journal Article