Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1990-12-31
pubmed:abstractText
The genome of equine infectious anemia virus (EIAV) contains several small open reading frames (ORFs), the importance of which in the development of the virus is not clear. We investigated the possibility that the largest of these ORFs (ORF S3) is expressed during the course of the viral infection. The ORF S3 information was expressed in Escherichia coli, and the antigen was used to raise monospecific antiserum. A 20-kDa protein expressed in cells producing EIAV was identified as the gene product of ORF S3. Furthermore, sera from EIAV-infected animals specifically recognized this protein, indicating that the ORF S3 antigen is expressed in vivo as well. A model for the expression of this new viral antigen is presented. The proposed splicing pattern is similar to that of the VEP-1 protein of maedi-visna-virus, which tempts us to speculate that ORF S3 defines the second exon of the EIAV Rev protein.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2423703, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2431539, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2535718, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2536163, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2549179, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2684654, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2780285, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2824840, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2841502, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2846892, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2849509, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2990908, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-2995822, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3003905, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3008154, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3012355, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3018743, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3031510, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3035786, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3490583, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3507693, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-3532863, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-4358259, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-5432063, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-6086324, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-6271633, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-6453650, http://linkedlifedata.com/resource/pubmed/commentcorrection/2173797-7063411
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-538X
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6319-24
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
The open reading frame ORF S3 of equine infectious anemia virus is expressed during the viral life cycle.
pubmed:affiliation
N.V. Innogenetics Research Laboratories, Antwerp, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't