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rdf:type |
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lifeskim:mentions |
umls-concept:C0021368,
umls-concept:C0038454,
umls-concept:C0521654,
umls-concept:C0591833,
umls-concept:C0927232,
umls-concept:C1517004,
umls-concept:C1549649,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C2349209,
umls-concept:C2728259
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pubmed:issue |
9
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pubmed:dateCreated |
2011-8-30
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pubmed:abstractText |
Evaluation of infarct volumes and infiltrating immune cell populations in mice after middle cerebral artery occlusion strongly implicates a mixture of both pathogenic and regulatory immune cell subsets that affect stroke outcome. Our goal was to evaluate the contribution of the well-described coinhibitory pathway, programmed death (PD)-1, to the development of middle cerebral artery occlusion.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD274,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Regulatory Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cd274 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/PDCD1LG2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Pdcd1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Pdcd1lg2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Peptides,
http://linkedlifedata.com/resource/pubmed/chemical/Programmed Cell Death 1 Ligand 2...,
http://linkedlifedata.com/resource/pubmed/chemical/Programmed Cell Death 1 Receptor,
http://linkedlifedata.com/resource/pubmed/chemical/TLR4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tlr2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1524-4628
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2578-83
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:21737801-Animals,
pubmed-meshheading:21737801-Antigens, CD274,
pubmed-meshheading:21737801-Antigens, CD80,
pubmed-meshheading:21737801-Antigens, Surface,
pubmed-meshheading:21737801-Apoptosis Regulatory Proteins,
pubmed-meshheading:21737801-B-Lymphocytes,
pubmed-meshheading:21737801-Brain Infarction,
pubmed-meshheading:21737801-Disease Models, Animal,
pubmed-meshheading:21737801-Inflammation,
pubmed-meshheading:21737801-Macrophages,
pubmed-meshheading:21737801-Membrane Glycoproteins,
pubmed-meshheading:21737801-Mice,
pubmed-meshheading:21737801-Mice, Knockout,
pubmed-meshheading:21737801-Microglia,
pubmed-meshheading:21737801-Peptides,
pubmed-meshheading:21737801-Programmed Cell Death 1 Ligand 2 Protein,
pubmed-meshheading:21737801-Programmed Cell Death 1 Receptor,
pubmed-meshheading:21737801-Signal Transduction,
pubmed-meshheading:21737801-Stroke,
pubmed-meshheading:21737801-T-Lymphocytes,
pubmed-meshheading:21737801-Toll-Like Receptor 2,
pubmed-meshheading:21737801-Toll-Like Receptor 4
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pubmed:year |
2011
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pubmed:articleTitle |
Programmed death-1 pathway limits central nervous system inflammation and neurologic deficits in murine experimental stroke.
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pubmed:affiliation |
DrMed, Neuroimmunology Research, R&D-31, Portland Veterans Affairs Medical Center, 3710 SW US Veterans Hospital Road, Portland, OR 97239, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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