Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1990-12-4
pubmed:abstractText
We report a case of primary splenic malignant fibrous histiocytoma that occurred in a 41-year-old man. Adjacent to the tumor there was a large calcified intrasplenic cyst. Despite splenectomy, postoperative radiation, and systemic chemotherapy, the patient died with metastatic tumor 6 months after diagnosis. Electron microscopic analysis of the tumor demonstrated subpopulations of tumor cells with fibroblastic or histiocytic features. Immunoperoxidase studies of frozen tumor tissue showed positive staining of both spindle and histiocytelike tumor cells with a large panel of monoclonal antibodies against antigens associated with the mononuclear phagocyte system. Expression of these antigens by the tumor supports a mononuclear phagocyte origin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0147-5185
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1061-70
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Primary tumor of spleen with morphologic features of malignant fibrous histiocytoma. Immunohistochemical evidence for a macrophage origin.
pubmed:affiliation
Department of Laboratory Medicine, Danbury Hospital, CT 06810.
pubmed:publicationType
Journal Article, Case Reports