Source:http://linkedlifedata.com/resource/pubmed/id/21734140
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2011-7-7
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pubmed:abstractText |
Measles has been a major killer among vaccine-preventable diseases in children < 5 years of age in developing countries. Despite progress in global efforts to reduce mortality, measles remains a public health problem. Hospital-based measles surveillance was conducted in Manhica, Mozambique (July 2001-September 2004). Suspected cases and community-based controls were enrolled, and blood was collected for immunoglobulin M (IgM) confirmation. Two hundred fifty-three suspected cases and 477 controls were enrolled, with 85% (216 of 253) cases reported during a measles outbreak. Measles-IgM confirmation was 30% among suspected cases and 5% in controls. Fifty-eight percent (14 of 24) of laboratory-confirmed cases had records indicating previous measles vaccination. Mortality was 3% (8 of 246) among cases and 1% among controls (6 of 426). Forty-five percent (33 of 74) of cases were < 24 months of age and 22% occurred in infants < 9 months of age and were associated with a high case-fatality rate (25%). Our data suggest that improved diagnostics, new tools to protect infants < 9 months of age, and a supplemental dose of measles vaccine could assist measles control.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1476-1645
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pubmed:author |
pubmed-author:AlonsoPedro LPL,
pubmed-author:CuberosLilianL,
pubmed-author:KotloffKaren LKL,
pubmed-author:LevineMyron MMM,
pubmed-author:MaceteEusébioE,
pubmed-author:MandomandoInácioI,
pubmed-author:NanicheDeniseD,
pubmed-author:NhalungoDelinoD,
pubmed-author:PasettiMarcela FMF,
pubmed-author:SanzSergiS,
pubmed-author:SigauqueBetuelB,
pubmed-author:VallèsXavierX
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pubmed:issnType |
Electronic
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
146-51
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pubmed:meshHeading |
pubmed-meshheading:21734140-Case-Control Studies,
pubmed-meshheading:21734140-Disease Outbreaks,
pubmed-meshheading:21734140-Humans,
pubmed-meshheading:21734140-Measles,
pubmed-meshheading:21734140-Measles Vaccine,
pubmed-meshheading:21734140-Mozambique,
pubmed-meshheading:21734140-Population Surveillance
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pubmed:year |
2011
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pubmed:articleTitle |
Assessment of the epidemiology and burden of measles in Southern Mozambique.
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pubmed:affiliation |
Centro de Investigação em Saúde da Manhiça (CISM), Maputo, Mozambique; Instituto Nacional de Saúde, Ministério de Saúde, Maputo, Mozambique. imandomando2004@yahoo.com.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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