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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1990-12-6
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pubmed:abstractText |
Islet cell carcinoma frequently produces more than one chemical product, although its clinical expression is usually restricted to a single hormone. We describe an unusual patient who presented with full-blown metastasizing gastrinoma. He was treated with cimetidine for five years and then streptozotocin therapy, which resulted in a regression in hepatomegaly and a fall in serum gastrin levels. Following one year's therapy with streptozotocin, he was admitted in hyperinsulinemic hypoglycemic stupor. This appears to be the first reported case of a "shift" from clinical gastrinoma to insulinoma possibly related to prolonged streptozotocin therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0192-0790
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
579-80
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2172360-Adenoma, Islet Cell,
pubmed-meshheading:2172360-Aged,
pubmed-meshheading:2172360-Gastrinoma,
pubmed-meshheading:2172360-Humans,
pubmed-meshheading:2172360-Insulinoma,
pubmed-meshheading:2172360-Liver Neoplasms,
pubmed-meshheading:2172360-Lymphatic Metastasis,
pubmed-meshheading:2172360-Male,
pubmed-meshheading:2172360-Pancreatic Neoplasms,
pubmed-meshheading:2172360-Stomach Neoplasms,
pubmed-meshheading:2172360-Streptozocin
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pubmed:year |
1990
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pubmed:articleTitle |
Insulinoma after streptozotocin therapy for metastatic gastrinoma: natural history or iatrogenic complication?
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pubmed:affiliation |
Department of Medicine H, Tel Aviv Medical Center, Israel.
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pubmed:publicationType |
Journal Article,
Case Reports
|