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pubmed-article:21722660pubmed:abstractTextTraffic related particulate matter air pollution is a risk factor for cardiovascular events; however, the biological mechanisms are unclear. We hypothesize that diesel exhaust (DE) inhalation induces up-regulation of inducible nitric oxide synthase (iNOS), which is known to contribute to vascular dysfunction, progression of atherosclerosis and ultimately cardiovascular morbidity and mortality.lld:pubmed
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pubmed-article:21722660pubmed:copyrightInfoCopyright © 2011 Elsevier Inc. All rights reserved.lld:pubmed
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pubmed-article:21722660pubmed:articleTitleExposure to diesel exhaust up-regulates iNOS expression in ApoE knockout mice.lld:pubmed
pubmed-article:21722660pubmed:affiliationDepartment of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada.lld:pubmed
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